Stiff-person syndrome

Stiff-person syndrome SPS is a rare acquired neurological disorder characterized by progressive muscle stiffness rigidity and repeated episodes of painful muscle spasms. Stiff-person syndrome SPS also known as stiff-man syndrome SMS 1 is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness.

Progression And Stages

Stiff-person syndrome SPS is a rare neurological disorder with features of an autoimmune disease.

. Symptoms may include extreme muscle stiffness rigidity and painful spasms in the trunk and limbs severely impairing mobility. SPS is strongly correlated with autoimmune diseases and it is usual to find high titers of antibodies against acid decarboxylase GAD65. SPS is labeled as a rare disease.

An autoimmune and neurological disorder that causes rigidity and spasms in the trunk and limbs. Muscular rigidity often fluctuates ie grows worse and then improves and usually occurs along with the muscle spasms. The stiffness primarily affects the truncal muscles and is superimposed by spasms resulting in postural deformities.

Symptoms include muscle spasms and rigidity. It causes progressive muscle stiffness and painful spasms that can be triggered by a variety of things including sudden movement cold temperature or unexpected loud noises. Muscle spasms can be so violent they can dislocate joints and even break bones.

SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise touch and emotional distress which can set off muscle spasms. Symptoms include stiffening in the torso and limbs along with episodes of severe muscle spasms. Muscle rigidity sporadic muscle spasms and chronic muscle pain characterize SPS.

Stiff-person syndrome SPS is a rare and disabling central nervous system disorder with no satisfactory treatment. Stiff person syndrome is more likely seen in people with certain types of diseases including. Why Choose Johns Hopkins.

Abnormal postures often hunched over and stiffened are characteristic of. Symptoms include muscle spasms hyper-rigidity debilitating pain and chronic anxiety. Stiff person syndrome SPS is a neurological disease with autoimmune features.

Stiff person syndrome SPS is a rare progressive syndrome that affects the nervous system specifically the brain and spinal cord. Autoimmune disorders including diabetes thyroiditis vitiligo and pernicious anemia. Stiff person syndrome SPS is a very rare disease affecting only one or two people per million.

Certain cancers including breast lung kidney thyroid colon and Hodgkins lymphoma. Learn more about the treatment and outlook for the condition here. Spasms can generate enough force to fracture bone.

Stiff person syndrome SPS is a rare autoimmune neurological disorder. But more people are affected than reported due to misdiagnoses. Medications and immunotherapy maybe prescribed with aqua occupational and physical therapy.

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